| 系统性红斑狼疮患者3种血清免疫因子水平检测的意义 |
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| 引用本文： | 刘惠容,曾东良,姜焕好,刘晓燕,徐惠莲.系统性红斑狼疮患者3种血清免疫因子水平检测的意义[J].检验医学与临床,2011,8(11):1295-1296. |
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| 作者姓名： | 刘惠容 曾东良 姜焕好 刘晓燕 徐惠莲 |
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| 作者单位： | 1. 广东省惠州市惠阳区妇幼保健院,516001
2. 广东省深圳市宝安区人民医院,518101 |
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| 摘 要： | 目的 探讨系统性红斑狼疮(SLE)患者血清中白细胞介素-6(IL-6)、IL-10、肿瘤坏死因子-α(TNF-α)的水平变化和意义.方法 分别用放射免疫分析和酶联免疫吸附试验(ELISA)对26例SLE患者IL-6、IL-10、TNF-α进行检测,并与20例健康者作比较.结果 SLE患者IL-6、IL-10和TNF-α水平明显高于健康组,差异具有统计学意义(P<0.01).结论 检测SLE患者血清IL-6、IL-10、TNF-α水平的变化对SLE患者的临床诊断和临床观察有临床价值.
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| 关 键 词： | 系统性红斑狼疮 白细胞介素-6 白细胞介素-10 肿瘤坏死因子-α |
Clinical signficance of determination of three serum immunological factors levels in patients with SLE |
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| LIU Hui-rong,ZENG Dong-liang,JIANG Huan-hao,LIU Xiao-yan,XU Hui-lian.Clinical signficance of determination of three serum immunological factors levels in patients with SLE[J].Laboratory Medicine and Clinic,2011,8(11):1295-1296. |
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| Authors: | LIU Hui-rong ZENG Dong-liang JIANG Huan-hao LIU Xiao-yan XU Hui-lian |
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| Institution: | LIU Hui-rong1,ZENG Dong-liang2,JIANG Huan-hao2,LIU Xiao-yan2,XU Hui-lian2(1.Maternal and Child Healthcare Centre of Huiyang District,Huizhou,Guangdong 516001,China,2.Deparment of Clinical Laboratory,Baoan Hospital of Shenzhen City,Guangdong 518101,China) |
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| Abstract: | Objective To explore the clinical signficance of the changes of serum IL-6,IL-10 and TNF-α in patients with SLE.Methods The level of TNF-α was detected by RIA,and levels of IL-6 and IL-10 were detected by ELISA in 26 patients with SLE and 20 controls.Results The levels of serum IL-6,IL-10,TNF-α in those patients with SLE were higher than those if control,the result was significantly different（P〈0.01）.Conclusion Detection of the changes in serum IL-6,IL-10 and TNF-α levels may have some clinical values in the clinical diagnosis and observation in patients with SLE. |
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| Keywords: | SLE IL-6 IL-10 TNF-α |
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