| 丙型病毒性肝炎患者血清瘦素的检测 |
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| 引用本文： | 孙树红,吴玉清,于华,牛爱荣.丙型病毒性肝炎患者血清瘦素的检测[J].标记免疫分析与临床,2006,13(3):129-130,140. |
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| 作者姓名： | 孙树红 吴玉清 于华 牛爱荣 |
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| 作者单位： | 青岛市中心医院核医学科,山东,青岛,266042;青岛市中心血站 |
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| 摘 要： | 研究丙肝患者血清leptin水平的变化。采用RIA检测65例丙肝组患者,80名对照组血清leptin水平,以及各种生化指标,比较各组的leptin水平以及leptin与各生化指标的相关性。结果显示慢性丙肝患者血清leptin水平较对照组明显升高(P<0.01);血清leptin水平与谷丙转氨酶(ALT)、谷草转氨酶(AST)呈显著性正相关(P<0.05);而与血糖(Glu)、总胆固醇(TC)无明显相关性(P>0.05)。慢性丙肝患者血清leptin水平升高且与肝脏炎症病变严重程度有关,leptin可以作为一个判断肝脏炎症严重程度的指标。
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| 关 键 词： | 丙型病毒性肝炎 瘦素 放射免疫分析法 |
| 文章编号： | 1006-1703（2006）03-0129-02 |
| 收稿时间： | 2006-03-10 |
| 修稿时间： | 2006-03-102006-05-17 |
Detection of Serum Leptin Levels in Patients with Viral Hepatitis C |
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| SUN Shu-hong,WU Yu-qing, YU Hua,et al..Detection of Serum Leptin Levels in Patients with Viral Hepatitis C[J].Labeled Immunoassays and Clinical Medicine,2006,13(3):129-130,140. |
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| Authors: | SUN Shu-hong WU Yu-qing YU Hua |
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| Institution: | Department of Nuclear Medicine,Qingdao Central Hospital ,Qingdao 266042,China |
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| Abstract: | To evaluate changes of serum leptin levels in patients with viral hepatitis C(HCV),serum leptin levels were determined by RIA in 65 patients with viral chronic hepatitis C and in 80 control subjects,liver function(ALT,AST),glucose(Glu),and total cholesterol(TC) were evaluated too.Campared with controls,the levels of serum leptin were significantly increased in patients with HCV(P<0.01).Serum leptin levels had remarkable positive correlations with ALT and AST(P<0.05),but not with Glu and TC(P>0.05).The levels of serum leptin increased in patients with HCV,which correlates positively with the severity of liver inflammation,so that leptin can be regarded as an index which reflects the severity of liver inflammation. |
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| Keywords: | Viral hepatitis C Leptin RIA |
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