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HP相关良性胃病患者血清胃泌素和胃动素的检测及意义
引用本文:何守搞,王超,潘小炎,黄赞松,周喜汉,尹毅霞.HP相关良性胃病患者血清胃泌素和胃动素的检测及意义[J].右江民族医学院学报,2008,30(2):183-184.
作者姓名:何守搞  王超  潘小炎  黄赞松  周喜汉  尹毅霞
作者单位:右江民族医学院附属医院消化内科,广西,百色,533000
摘    要:目的探讨血清胃泌素和胃动素的释放与幽门螺杆菌(HP)相关性胃炎及消化性溃疡的关系。方法采用放射免疫计数仪对268例HP阳性、183例HP阴性及150例HP清除后良性胃病患者血中的胃动素和胃泌素水平进行检测。结果HP阳性的慢性浅表性胃炎(CSG)、胃溃疡(GU)、十二指肠球部溃疡(DU)患者的血清胃泌素和胃动素水平:DU>GU>CSG(P<0.01)。HP阳性患者血清胃泌素水平较HP阴性患者高(P<0.05或0.01),而胃动素水平恰好相反(P<0.01)。HP清除后病人血清胃动素水平升高、胃泌素水平下降(P<0.01)。结论HP感染可引起血清胃泌素水平升高、胃动素水平降低。

关 键 词:螺杆菌  幽门  胃炎  胃溃疡  十二指肠溃疡  胃泌素类  促胃动素
文章编号:1001-5817(2008)02-0183-02
修稿时间:2007年10月25

The detection of serum gastrin and motilin in patients with benign Hp-associated gastric diseases
HE Shou-gao,WANG Chao,PAN Xiao-yan,HUANG Zan-song,ZHOU Xi-han,YIN Yi-xia.The detection of serum gastrin and motilin in patients with benign Hp-associated gastric diseases[J].Journal of Youjiang Medical College For Nationalities,2008,30(2):183-184.
Authors:HE Shou-gao  WANG Chao  PAN Xiao-yan  HUANG Zan-song  ZHOU Xi-han  YIN Yi-xia
Institution:HE Shou-gao,WANG Chao,PAN Xiao-yan,HUANG Zan-song,ZHOU Xi-han,YIN Yi-xia (Department of Gastroenterology,Affiliated Hospital of Youjiang Medical College for Nationalities,Baise,Guangxi 533000,China)
Abstract:Objective To investigate the relationship between the secretion of serum gastrin and motilin and Helicobacter pylori(Hp)-associated chronic gastritis and peptic ulcer.Methods 601 patients with benign gastric disease,including 268 cases with Hp positive(of 150 patients with Hp eradication) and 183 with Hp negative were involved in this study.Serum gastrin and motilin were measured by using radioimmunoassay.Results The levels of serum gastrin and motilin in Hp positive patients with chronic superficial gastri...
Keywords:Helicobacter pylori  gastritis  stomach ulcer  duodenal ulcer  gastrins  motilin  
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