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Occurrence of neuropeptide Y (NPY)-like immunoreactivity in catecholamine neurons in the human medulla oblongata |
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| Authors: | T. Hökfelt J.M. Lundberg H. Lagercrantz K. Tatemoto V. Mutt J. Lindberg L. Terenius B.J. Everitt K. Fuxe L. Agnati M. Goldstein |
| Affiliation: | 1. Departments of Histology, Pharmacology, Neurophysiology, Biochemistry II and Forensic Medicine, Karolinska Institutet, USA;2. Department of Pediatrics, Karolinska Hospital, Stockholm Sweden;3. Department of Psychiatry, New York University Medical Center, New York, NY U.S.A. |
| Abstract: | We report here the coexistence of a neuropeptide and catecholamines in neurons of the human brain. Using indirect immunofluorescence histochemistry, combined with elution and restaining experiments, neurons in the medulla oblongata of man were demonstrated to contain both a neuropeptide Y-like peptide and the catecholamine synthesizing enzyme tyrosine hydroxylase. |
| Keywords: | neuropeptide Y catecholamines coexistence human brain immunofluorescence |
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