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长托宁、地塞米松预注抑制芬太尼咳嗽反射
引用本文:施福安,陈箴,李可军,李忠,艾君,严朝阳. 长托宁、地塞米松预注抑制芬太尼咳嗽反射[J]. 中国现代医生, 2008, 46(7): 113-114
作者姓名:施福安  陈箴  李可军  李忠  艾君  严朝阳
作者单位:湖北省安陆市普爱医院麻醉科,湖北安陆,432600
摘    要:目的观察长托宁、地塞米松预注抑制芬太尼咳嗽反射的有效性。方法选择全麻病人100例,随机分为实验组(Ⅰ组)和对照组(Ⅱ组),每组50例。Ⅰ组病人于芬太尼静注前10min静注长托宁0.5mg、地塞米松5mg,观察两组病人静注分太尼后1min发生反射性咳嗽的例数(发生率)并进行比较。结果Ⅰ组病人发生发射性咳嗽4例(8%);Ⅱ组病人发生反射性咳嗽18例(36%),两组有极显著性差异(P〈0.01)。结论长托宁、地塞米松预注能够抑制芬太尼的咳嗽反射。

关 键 词:长托宁  地塞米松  芬太尼  咳嗽反射
文章编号:1673-9701(2008)07-113-02
修稿时间:2007-01-03

Pre-injection of Penehyclidine and Dexamethasone in Restraining Cough Reflex Caused by Fentanyl
SHI Fuan,CHEN Zhen,LI Kejun,LI Zhong,Ai Jun,YAN Chaoyang. Pre-injection of Penehyclidine and Dexamethasone in Restraining Cough Reflex Caused by Fentanyl[J]. , 2008, 46(7): 113-114
Authors:SHI Fuan  CHEN Zhen  LI Kejun  LI Zhong  Ai Jun  YAN Chaoyang
Affiliation:(Department of Anesthesiology, Pu'ai Hospital of Anlu, Hubei 432600)
Abstract:Objective To observe the effectiveness of pre-injection of penehyclidine and dexamethasone in restraining cough reflex caused by fentanyl. Methods 100 ehosed patients of general anesthesia were randomly divided into experimental group (Group Ⅰ ) and comparison group(Group Ⅱ ) ,50 patients in each group. Patients in group Ⅰ are mainlined 0.5 mg penehyelidine and 5 mg dexamethasone at 10 min before mainlined fentanyl,then the cough reflex eases(incidence) in two groups were observed and compared at 1 min after patients being mainlined fentanyl. Results There were four cough reflex eases(8%) in Group Ⅰ and 18 eases(36%) in Group Ⅱ. The difference between two groups was very significant(P〈 0.01 ). Conclusion Pre-injection of penehyelidine and dexamethasone can restrain cough reflex caused by fentanyl.
Keywords:Penehyelidine  Dexamethasonum  Fentanyl  Cough reflex
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