| 熄风胶囊对癫痫小鼠海马一氧化氮合酶活力的影响 |
| |
| 引用本文： | 熊杰,马融,杨常泉,张果忠.熄风胶囊对癫痫小鼠海马一氧化氮合酶活力的影响[J].山西中医,2003,19(2):52-53. |
| |
| 作者姓名： | 熊杰 马融 杨常泉 张果忠 |
| |
| 作者单位： | 1. 中国人民武装警察部队医学院附属医院,天津,300162
2. 天津中医学院第一附属医院 |
| |
| 基金项目： | 天津市教育厅中标科研课题 (中标号 :98C0 34 ) |
| |
| 摘 要： | 采用NADPH—黄递酶染色法，探讨不同浓度的中成药熄风胶囊对戊四唑致痫小鼠海马不同亚区一氧化氮合酶(NOS)活力的影响。结果：实验组小鼠灌服不同浓度的熄风胶囊浓缩液后，其海马不同亚区NOS活力均高于模型组。提示，该药对癫痫小鼠海马神经元有保护作用．此结果可能是其治疗癫痫的机理之一。
|
| 关 键 词： | 熄风胶囊 中药制剂 癫痫 一氧化氮合酶 神经元 动物实验 |
| 文章编号： | 1000-7156(2003)02-0052-02 |
| 修稿时间： | 2002年6月22日 |
The Effect of Xifeng Capsule(熄风胶囊)on the Activity of Nitric Oxide Synthase (NOS) in Hippocampal Subareas of Epileptic Mice |
| |
| XIONG Jie ,MA Rong,YANG Cang-quan,et al.The Effect of Xifeng Capsule(熄风胶囊)on the Activity of Nitric Oxide Synthase (NOS) in Hippocampal Subareas of Epileptic Mice[J].Shanxi Journal of Traditional Chinese Medicine,2003,19(2):52-53. |
| |
| Authors: | XIONG Jie MA Rong YANG Cang-quan |
| |
| Institution: | XIONG Jie *,MA Rong,YANG Cang-quan,et al |
| |
| Abstract: | The effect of different concentration of Xifeng Capsule on the activity of NOS in hippocamal subareas of epileptic mice was detected by NADPH diaphorase staining.The epilepsia model of mouse was made by pentylenetetrzol.Result:The activity of NOS in hippocamal subareas of the treatment groups was much higher than that in the control group.It suggested that Xifeng Capsule could protect the nerve cells in hippocamal subareas of epileptic mice.This may be one of the mechanisms of the therapy. |
| |
| Keywords: | Xifeng Capsule epilepsia hippocampus mouse nitric oxide synthase experimental research |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
