幽门螺杆菌感染与慢性肝病及肝源性溃疡的相关性研究

目的：探讨慢性肝病患者的幽门螺杆菌（HP）感染情况及HP感染与肝源性溃疡的关系。方法：268例胃镜检查患者同时采用血清学、尿素酶试验、组织学染色行HP检查。结果：慢性肝病患者HP感染率为58．70％，非慢性肝病患者为54．62％（P＞0．05）；肝源性溃疡患者为56．52％，消化性溃疡患者为92．06％（P＜0．05）。轻、中、重三组食管静脉曲张患者溃疡发生率分别为11．11％、43．48％、73．91％。结论：慢性肝病患者HP感染率与非慢性肝病患者无显著性差异；肝源性溃疡患者HP感染率明显少于消化性溃疡患者；食管静脉曲张程度越高，溃疡发生率越高，HP感染不是其主要病因。

The Study on the Helicobacter Pylori Infection in Chronic Liver Patients and the Relationship Between Helicobacter Pylori Infection and Cirrhosis Peptic Ulcer

Purpose: In order to study the helicobacter pylori(HP) infection in patients with chronic liver and the relationship betwern HP infection and cirrhosis peptic ulcer. Methods: The HP infection of 268 esophagogastroscopy cases were analyzed on the base of founding of serolgical test, rapid ureas test and histological stain. Results: The infectious rate of HP in chronic liver disease patients is 58.70%, in non chronic liver disease patients is 54.62%(P>0.05). The infections rate of HP in cirrhosis peptic ulcer patients is 56.52%, it is 92.06% in peptic ulcer patients(P<0.05). The incidence rate of ulcer is 11.11% in gentle esophageal varicose group, 43.48% in mind esophageal varicose group, 73.91% in heavy esophageal varicose group. Conclusion: There is no significant difference between the HP infection in chronic liver disease group and non chronic liver disease group. HP infection in cirrhosis peptic ulcer group is visibly less than patients in peptic ulcer group the higher degree of the esophageal varices, the more peptic ulcer happen. The HP infection is not the leading reason.