| 硫酸二甲酯的遗传毒效应研究 |
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| 引用本文： | 慈杰元 张慧泉. 硫酸二甲酯的遗传毒效应研究[J]. 工业卫生与职业病, 1996, 22(2): 75-76 |
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| 作者姓名： | 慈杰元 张慧泉 |
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| 作者单位： | 黑龙江省哈尔滨劳动卫生职业病研究所 |
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| 摘 要： | 本文研究结果表明，硫酸二甲酯对职业接触人群外周血淋巴细胞以及实验动物骨髓细胞有明显的致突变作用。Ａｍｅｓ试验阳性证明：在不需要诱导活化情况下，硫酸二甲酯通话甩基因突变，是一种直接致突变剂。
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| 关 键 词： | 硫酸二甲酯 染色体畸变 透变性 |
STUDY ON GENETIC TOXICITY EFFECT OF DIMETHYL SULFATE |
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| Ci jieyuan et al. STUDY ON GENETIC TOXICITY EFFECT OF DIMETHYL SULFATE[J]. Industrial Health and Occupational Diseases, 1996, 22(2): 75-76 |
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| Authors: | Ci jieyuan et al |
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| Abstract: | The results of this study showed that dimethyl sulfate (DMS) can cause obvious mutagenesis of lymphocytes in peripheral blood of occupationally exposed population and marrow cells of exper imental animals. Positive results of Ames test also indicated that DMS can induce genic mutagenesis witbout S9, and is a direct mutagenic agent. |
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| Keywords: | Dimethyl sulfate Chromosome aberration Mutagenicity |
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