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Ropivacaine Induces Cell Cycle Arrest in the G0/G1 Phase and Apoptosis of PC12 Cells via Inhibiting Mitochondrial STAT3 Translocation |
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| Authors: | Zeng Lian Li Aohan Zhang Zhen Zhang Fuyu Chen Huaxian Wang Ying Ding Xudong Luo Huiyu |
| Affiliation: | 1.Department of Anesthesiology, Xiangyang Key Laboratory of Movement Disorders, Xiangyang No.1 People’s Hospital, Hubei Clinical Research Center of Parkinson’s Disease, Hubei University of Medicine, Hubei, China ;2.Department of Oncology, Xiangyang No.1 People’s Hospital, Hubei University of Medicine, Hubei, China ;3.Department of Rehabilitation Medicine, Xiangyang No.1 People’s Hospital, Hubei University of Medicine, Hubei, China ; |
| Abstract: | Inflammation - STAT3 has neuroprotective effect via non-canonical activation and mitochondrial translocation, but its effect on ropivacaine-induced neurotoxicity remains unclear. Our previous study... |
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