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Risk of Systemic Adverse Events after Intravitreal Bevacizumab,Ranibizumab, and Aflibercept in Routine Clinical Practice
Authors:Maya H. Maloney  Stephanie R. Payne  Jeph Herrin  Lindsey R. Sangaralingham  Nilay D. Shah  Andrew J. Barkmeier
Affiliation:1. Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota;2. Department of Ophthalmology, Kaiser Permanente, Vacaville, California;3. Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota;4. Yale School of Medicine, Yale University, New Haven, Connecticut;5. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota;6. Division of Health Care Policy and Research, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota;7. OptumLabs, Cambridge, Massachusetts
Abstract:
Keywords:anti-VEGF  aflibercept  ranibizumab  bevacizumab  age-related macular degeneration  diabetic retinopathy  retinal vein occlusion  CI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0055"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  confidence interval  CVD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0065"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  cerebrovascular disease  DME"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0075"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  diabetic macular edema  DRD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0085"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  diabetic retinal disease  FDA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0095"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Food and Drug Administration  HR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0105"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  hazard ratio  ICD-9"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0115"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  International Classification of Diseases 9th Revision  ICD-10"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0125"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  International Classification of Diseases 10th Revision  IQR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0135"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  interquartile range  MI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0145"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  myocardial infarction  nAMD"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0155"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  neovascular age-related macular degeneration  RVO"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0165"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  retinal vein occlusion  SAE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0175"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  systemic adverse event  VEGF"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0185"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  vascular endothelial growth factor
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