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妇炎消胶囊质量标准的研究
引用本文:陈惠玲,曾荣洁.妇炎消胶囊质量标准的研究[J].中国药品标准,2014,15(4):272-275.
作者姓名:陈惠玲  曾荣洁
作者单位:厦门市药品检验所,厦门361012
摘    要:目的:提高完善妇炎消胶囊的质量标准。方法:采用薄层色谱法鉴别败酱草;采用高效液相色谱法测定大黄中大黄素和大黄酚的含量;采用高效液相色谱法测定牡丹皮中芍药苷的含量。结果:大黄素在0.0080~0.2012μg范围内呈良好的线性关系(r=1.0000),平均回收率为98.1%(RSD=3.0%,n=9);大黄酚在0.0262~0.6550μg范围内呈良好的线性关系(r=1.0000),平均回收率为102.4%( RSD=2.6%,n=9);芍药苷在0.0997~1.9937μg范围内呈良好的线性关系(r=1.0000),平均回收率为103.3%( RSD=1.5%,n=9)。结论:建立的方法准确可靠,适用于妇炎消胶囊的质量控制。

关 键 词:妇炎消胶囊  大黄素  大黄酚  芍药苷  败酱草  质量标准
收稿时间:2013/11/8 0:00:00
修稿时间:2014/6/24 0:00:00

Study on Quality Standards for Fuyanxiao Capsules
Authors:Chen Huiling and Zeng Rongjie
Institution:( Xiamen Institute for Drug Control, Xiamen 361012 )
Abstract:Objective:To establish quality standard for Fuyanxiao Capsules.Methods: Herba Patriniae was identified by TLC; the concentration of emodin ,chrysophanol and paeoniflorin were determined by HPLC.Results:The calibration curveof emodin was linear within the range of 0.0080-0.2012 μg(r=1.0000), the average recovery was 98.1%with RSD of 3.0%(n=9);the range of chry-sophanol was 0.0262-0.6550 μg(r=1.0000),the average recovery was 102.4%with RSD at 2.6%(n=9) and that of paeoniflorin was 0.0997-1.9937 μg(r=1.0000), average recovery was 103.3%and RSD of 1.5%(n=9).Conclusion:The methods are sen-sitive,accurate and suitable for the quality control of Fuyanxiao Capsules.
Keywords:Fuyanxiao Capsules  emodin  chrysophanol  paeoniflorin  herba patriniae  quality control
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