妇炎消胶囊质量标准的研究 |
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引用本文: | 陈惠玲,曾荣洁.妇炎消胶囊质量标准的研究[J].中国药品标准,2014,15(4):272-275. |
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作者姓名: | 陈惠玲 曾荣洁 |
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作者单位: | 厦门市药品检验所,厦门361012 |
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摘 要: | 目的:提高完善妇炎消胶囊的质量标准。方法:采用薄层色谱法鉴别败酱草;采用高效液相色谱法测定大黄中大黄素和大黄酚的含量;采用高效液相色谱法测定牡丹皮中芍药苷的含量。结果:大黄素在0.0080~0.2012μg范围内呈良好的线性关系(r=1.0000),平均回收率为98.1%(RSD=3.0%,n=9);大黄酚在0.0262~0.6550μg范围内呈良好的线性关系(r=1.0000),平均回收率为102.4%( RSD=2.6%,n=9);芍药苷在0.0997~1.9937μg范围内呈良好的线性关系(r=1.0000),平均回收率为103.3%( RSD=1.5%,n=9)。结论:建立的方法准确可靠,适用于妇炎消胶囊的质量控制。
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关 键 词: | 妇炎消胶囊 大黄素 大黄酚 芍药苷 败酱草 质量标准 |
收稿时间: | 2013/11/8 0:00:00 |
修稿时间: | 2014/6/24 0:00:00 |
Study on Quality Standards for Fuyanxiao Capsules |
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Authors: | Chen Huiling and Zeng Rongjie |
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Institution: | ( Xiamen Institute for Drug Control, Xiamen 361012 ) |
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Abstract: | Objective:To establish quality standard for Fuyanxiao Capsules.Methods: Herba Patriniae was identified by TLC; the concentration of emodin ,chrysophanol and paeoniflorin were determined by HPLC.Results:The calibration curveof emodin was linear within the range of 0.0080-0.2012 μg(r=1.0000), the average recovery was 98.1%with RSD of 3.0%(n=9);the range of chry-sophanol was 0.0262-0.6550 μg(r=1.0000),the average recovery was 102.4%with RSD at 2.6%(n=9) and that of paeoniflorin was 0.0997-1.9937 μg(r=1.0000), average recovery was 103.3%and RSD of 1.5%(n=9).Conclusion:The methods are sen-sitive,accurate and suitable for the quality control of Fuyanxiao Capsules. |
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Keywords: | Fuyanxiao Capsules emodin chrysophanol paeoniflorin herba patriniae quality control |
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