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阿立哌唑与奎硫平治疗首发精神分裂症对照分析
引用本文:彭星,黄艳,刘秀英. 阿立哌唑与奎硫平治疗首发精神分裂症对照分析[J]. 临床精神医学杂志, 2007, 17(5): 329-330
作者姓名:彭星  黄艳  刘秀英
作者单位:湖南衡阳市第一精神病医院,421002;湖南衡阳市第一精神病医院,421002;湖南衡阳市第一精神病医院,421002
摘    要:目的:评价阿立哌唑与奎硫平对治疗首发精神分裂症患者的有效性和安全性。方法:对85例首发精神分裂症患者,随机分为阿立哌唑组及奎硫平组进行治疗,分别在治疗前及治疗2,4,8周末采用阳性与阴性症状量表(PANSS)评定临床疗效,用治疗中出现的症状量表(TESS)评定药物不良反应。结果:阿立哌唑能有效治疗首发精神分裂症的阳性症状及阴性症状,疗效与奎硫平相当,不良反应较奎硫平更少。结论:阿立哌唑是一种有效而安全的新型抗精神病药。

关 键 词:精神分裂症  阿立哌唑  奎硫平
文章编号:1005-3220(2007)05-0329-02
收稿时间:2006-09-25
修稿时间:2006-09-25

A clinical analysis of aripiprazole and quetiapine in treatment of first episode schizophrenia
PENG Xing,HUANG Yan,LIU Xiu-ying. A clinical analysis of aripiprazole and quetiapine in treatment of first episode schizophrenia[J]. Journal of Clinical Psychological Medicine, 2007, 17(5): 329-330
Authors:PENG Xing  HUANG Yan  LIU Xiu-ying
Affiliation:The First Mental Hospital of Hengyang City, Hengyang 421002, China
Abstract:Objective:To evaluate efficacy and safety of aripiprazole and quetiapine in the treatment of schizophrenia.Method:Eighty-five patients with first episode schizophrenia were randomly divided into aripiprazole group or quetiapine group.Positive and negative symptom scale(PANSS)and treatment emergent symptom scale(TESS)were used to evaluate the efficacy and adverse events of drugs before and after 2,4,8 weeks of treatments.Results:Aripiprazole had similar effects to quetiapine in the treatment of schizophrenia with positive and negative symptoms,with fewer side effects.Conclusion:Aripiprazole is one of effective and safe drugs in the treatment of schizophrenia.
Keywords:schizophrenia  aripizole  quetiapine
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