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鼻咽癌调强放射治疗与常规放疗的剂量学比较
引用本文:张福正,邹勤舟,黄剑峰,车俊,范强,楚建军,赵的非,贺蓓娃. 鼻咽癌调强放射治疗与常规放疗的剂量学比较[J]. 中国医药, 2010, 5(12): 1182-1183. DOI: 10.3760/cma.j.issn.1673-4777.2010.12.032
作者姓名:张福正  邹勤舟  黄剑峰  车俊  范强  楚建军  赵的非  贺蓓娃
作者单位:江苏省无锡市第四人民医院肿瘤放疗科,214062
摘    要:目的 比较鼻咽癌调强放疗和常规放疗时肿瘤和正常组织受照剂量的差异.方法 用CMS逆向治疗计划系统分别对30例T3N1M0鼻咽癌患者进行调强放疗和常规放疗计划设计,计算肿瘤和正常组织受照射剂量.结果 调强放疗与常规放疗肿瘤所接受的剂量无明显差别(P>0.05),射野内垂体和左右侧腮腺、颞叶、颞颌关节受照剂量低于常规放疗[(48.6±2.5)Gy比(62.5±4.8)Gy;(41.3±2.7)Gy比(67.7±2.6)Gy,(41.5±4.2)Gy比(66.0±2.7)Gy;(25.4±6.2)Gy比(56.3±1.4)Gy,(25.4±6.6)Gy比(56.1±1.5)Gy;(41.1±4.2)Gy比(62.5±5.9)Gy,(41.9±4.8)Gy比(60.1±10.0)Gy;P<0.05].结论 鼻咽癌调强放疗与常规放疗相比,肿瘤靶区剂量精确可靠,正常组织受照剂量得到有效控制.

关 键 词:鼻咽肿瘤  常规放疗  调强放疗  放射治疗剂量

Comparison of intensity modulated radiation therapy and conventional radiation therapy
ZHANG Fu-zheng,ZOU Qin-zhou,HUANG Jian-feng,CHE Jun,FAN Qiang,CHU Jian-jun,ZHAO Di-fei,HE Bei-wa. Comparison of intensity modulated radiation therapy and conventional radiation therapy[J]. China Medicine, 2010, 5(12): 1182-1183. DOI: 10.3760/cma.j.issn.1673-4777.2010.12.032
Authors:ZHANG Fu-zheng  ZOU Qin-zhou  HUANG Jian-feng  CHE Jun  FAN Qiang  CHU Jian-jun  ZHAO Di-fei  HE Bei-wa
Affiliation:ZHANG Fu-zheng(Department of Radiation Oncology, Fourth Hospital of Wuxi City, Jiangsu Province, Wuxi 214062, China ) ZOU Qin-zhou(Department of Radiation Oncology, Fourth Hospital of Wuxi City, Jiangsu Province, Wuxi 214062, China ) HUANG Jian-feng(Department of Radiation Oncology, Fourth Hospital of Wuxi City, Jiangsu Province, Wuxi 214062, China ) CHE Jun(Department of Radiation Oncology, Fourth Hospital of Wuxi City, Jiangsu Province, Wuxi 214062, China ) FAN Qiang(Department of Radiation Oncology, Fourth Hospital of Wuxi City, Jiangsu Province, Wuxi 214062, China ) CHU Jian-jun(Department of Radiation Oncology, Fourth Hospital of Wuxi City, Jiangsu Province, Wuxi 214062, China ) ZHAO Di-fei(Department of Radiation Oncology, Fourth Hospital of Wuxi City, Jiangsu Province, Wuxi 214062, China ) HE Bei-wa (Department of Radiation Oncology, Fourth Hospital of Wuxi City, Jiangsu Province, Wuxi 214062, China )
Abstract:Objective To study and compare the dose difference of intensity modulated radiation therapy (IMRT) and conventional radiation therapy(CRT) affecting tumor and normal tissues. Methods Thirty nasopharyngeal carcinoma patients in stage T3N1M0 received IMRT and CRT with CMS system. The dose affecting tumor and normal tissues was calculated respectively. Results There was no significant difference of the dose between IMRT and CRT, but the dose affecting the normal tissue was lower in IMRT than that in CRT. Conclusions The dose distribution to tumor target area is more precise with IMRT than that with CRT. The dose to the normal tissues is controlled more effectively with IMRT than that with CRT.
Keywords:Nasopharyngeal neoplasms  Conventional radiation therapy  Intensity modulated radiation therapy  Radiotherapy dosage
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