Interaction between Alpha-Fetoprotein Gene and Gonadotropin-Releasing Hormone and Effects on Brain Sexual Differentation: Molecular Function and Biological Process

Brain sexual differentiation is a present focus in sexuality research. Within the process, the alpha-fetoprotein gene (AFP) and gonadotropin-releasing hormone (GnRH) are found to be interacted and cause several effect on the sexual differentiation in animal model. However, the actual mechanism and interaction in human has never been clarified. Here, the author used a new gene ontology technology to predict the molecular function and biological process of the interaction between GnRH and AFP in human.