| 葡萄糖、胰岛素对内皮细胞一氧化氮和内皮素1分泌影响的对比研究 |
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| 引用本文： | 柴伟栋,陈家伟,沈捷,崔毓桂,马向华,倪黎,汪承亚. 葡萄糖、胰岛素对内皮细胞一氧化氮和内皮素1分泌影响的对比研究[J]. 中华内分泌代谢杂志, 2004, 20(2): 170-171 |
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| 作者姓名： | 柴伟栋 陈家伟 沈捷 崔毓桂 马向华 倪黎 汪承亚 |
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| 作者单位： | 1. 210029,南京医科大学第一附属医院内分泌科
2. 210029,南京医科大学第一附属医院中心实验室 |
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| 摘 要： | 牛主动脉内皮细胞体外培养时 ,高浓度葡萄糖和胰岛素促使内皮素 1水平升高而降低一氧化氮水平 ,提示这些变化能促进糖尿病性高血压的发生发展。
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| 关 键 词： | 一氧化氮 内皮缩血管肽1 糖尿病 高血压 |
| 修稿时间： | 2002-08-30 |
Comparative study on the secretions of NO and endothelin-1 of vascular endothelial cells by glucose and insulin |
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| CAI Wei-dong,CHEN Jia-wei,SHEN Jie,CUI Yu-gui,MA Xiang-hua,NI Li,WANG Cheng-ya. Comparative study on the secretions of NO and endothelin-1 of vascular endothelial cells by glucose and insulin[J]. Chinese Journal of Endocrinology and Metabolism, 2004, 20(2): 170-171 |
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| Authors: | CAI Wei-dong CHEN Jia-wei SHEN Jie CUI Yu-gui MA Xiang-hua NI Li WANG Cheng-ya |
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| Affiliation: | CAI Wei-dong*,CHEN Jia-wei,SHEN Jie,CUI Yu-gui,MA Xiang-hua,NI Li,WANG Cheng-ya.*Department of Endocrinology,The First Affiliated Hospital,Nanjing Medical University,Nanjing 210029 |
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| Abstract: | High concentrations of glucose and insulin stimulated endothelin-1 production and decreased nitric oxide production in cultured bovine aorta endothelia, which seem to accelerate the development of hypertension in diabetic animals. |
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| Keywords: | Nitric oxide Endothelin-1 Diabetes mellitus Hypertension |
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