危重患儿80例肝功能、心肌酶谱临床分析

目的探讨肝功能、心肌酶谱在危重患儿病情变化中的意义。方法小儿危重病例评分≤80分患儿80例作为危重组，其中18例为极危重患儿（≤70分）；非危重患儿（〉80分）80例作为对照组，所有病例于入院1h内作相应处理后，测定其肝功能、心肌酶谱。结果80例危重组患儿中，ALT升高52例（65．0％），γ—GT升高55例（68．8％），TBA升高46例（48．8％），ALB下降39例（48．8％）；AST升高61例（76．2％），CK升高62例（77．5％），CK—MB升高68例（85．0％），LDH升高52例（65．0％），α—HBDH升高54例（67．5％）。非危重组ALT升高9例（11．25％），γ—GT升高3例（3，75％），TBA升高2例（2，5％），ALB下降11例（13．8％）；AST升高13例（16．2％），CK升高9例（11．2％），CK—MB升高11例（13．8％），LDH升高8例（10．0％）α—HBDH升高12例（15．O％）。极危重组患儿肝功能、心肌酶谱改变高于危重组患儿，而危重组患儿肝功能、心肌酶谱改变均高于非危重组患儿（均P〈0．05）。结论肝功能、心肌酶谱不只是肝脏、心肌损伤的指标，而且可作为危重患儿的辅助诊断指标，对判断病情严重程度及预后有重要的临床指导意义。

Analysis of the liver function and myocardial enzymes in 80 critically ill children

Objective To investigate the clinical significance of liver function and myocardial enzyme indexes in critically ill children, by the determination of liver function and myocardial enzymes in critically ill children. Methods Select children,with the application of pediatric critical illness scoring system to rate and decided 80 cases of critically ill children as a critical group,of which 18 cases were very critically ill children. And chose 80 cases of non-critically ill children as a control group. Determine liver function and myocardial enzymes of the cases given the appropriate treatment within the first hour of being hospitalized. Results The most critical group in children with the changes of liver function and myocardial enzyme in children above the critical group, while the critical group above the non-critical group, the greater the change, statistically significant (all P ＜ 0.05). Conclusion The liver function and myocardial enzymes not only could be used as indicators of the liver and myocardial injury,but also auxiliary diagnostic index in critically ill children,and had important clinical significance in judging the severity and prognosis of the disease.