妊娠梅毒173例临床分析

目的探讨妊娠梅毒临床特点及影响妊娠结局的因素。方法 173例经血清学检查确诊为妊娠梅毒孕产妇,依据妊娠期是否抗梅毒治疗分为治疗组(141例)及未治疗组(32例)。比较两组孕产妇的妊娠结局、围生儿预后及新生儿先天梅毒的发生情况。结果治疗组足月产发生率和未治疗组足月产发生率,两组比较,差异有极显著性(P<0.05);而死胎死产及先天梅毒儿发生率,未治疗组显著高于治疗组,两组比较,差异有极显著性(P<0.01)。结论有效规范抗梅毒治疗是改善妊娠梅毒患者妊娠结局、围生儿预后以及降低先天梅毒患儿发生率的关键。

Clinical Analysis of 173 Pregnant Women Infected by Syphilis

Objective To investigate the clinical characteristic of syphilis in pregnant women and the effect on the perinatal outcomes.Methods One hundred and seventy-three pregnant women with syphilis by serological testing were divided into two groups,group A(n=141):treated with anti-syphilis therapy and group B(n=32) :untreated group.The pregnant outcomes、 perinatal prognosis and congenital syphilis were compared between two groups.Results A very signif icant difference of incidence was found between the treated group and untreated group of term delivery(P<0.005).The incidences of fetal death、stillbirth and congenital syphilis in group A were signifi cantly lower than group B(P<0.01).Conclusions Effective anti-syphilis therapy is the key to improve the outcomes of pregnancy with syphilis,prognosis of neonates and reducing incidence of congenital syphilis.