Trichinella infection and clinical disease |
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Authors: | Clausen MR; Meyer CN; Krantz T; Moser C; Gomme G; Kayser L; Albrectsen J; Kapel CM; Bygbjerg IC |
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Institution: | Departments of Infectious Diseases, Microbiology, Rheumatology and Immunology, and Pathology, Rigshospitalet, University of Copenhagen, Denmark; Danish Center for Experimental Parasitology, Royal Veterinary and Agricultural University, Copenhagen, Denmark; Corresponding author at: Department of Infectious Diseases M 7722, Rigshopitalet, DK-2100 Copenhagen, Denmark |
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Abstract: | Trichinellosis is caused by ingestion of insufficiently cooked meat
contaminated with infective larvae of <it>Trichinella</it>
species. The clinical course is highly variable, ranging from no apparent
infection to severe and even fatal disease. We report two illustrative
cases of trichinellosis. Returning to Denmark a few days after having eaten
roasted pork in the Republic of Serbia, a female patient suffered from
severe vomiting, epigastric pain, diarrhoea, and later myalgia, generalized
oedema, and prostration. A biopsy showed heavy infestation with
<it>Trichinella spiralis</it>, 2000 larvae/g of muscle.
Life-threatening cardiopulmonary, renal and central nervous system
complications developed. The patient recovered after several months. Her
husband, who also ate the pork, did not have clinical symptoms, but an
increased eosinophil count and a single larva in a muscle biopsy confirmed
infection. The epidemiology, clinical manifestations, diagnosis, treatment
and prevention of trichinellosis are reviewed.
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