Abstract: | Acetylcholinesterase activity differs in the membranes of young, mature, and old human erythrocytes: It is highest in the mature and lowest in the old cells. The enzymes in young and mature erythrocytes is in the form of three, but in the old cells in the form of two molecular components. The results suggest that changes in the structural organization of acetylcholinesterase in the erythrocyte membrane have a direct bearing on the aging of red blood cells.Laboratory of Biochemistry, Institute of Hematology and Blood Transfusion, Leningrad. (Presented by Academician of the Academy of Medical Sciences of the USSR V. S. Il'in.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 10, pp. 1198–1200, October, 1976. |