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| 用新型激光衍射法研究新生在体红细胞变形和取向的变化 | |
| 引用本文： | 曾柱,杨海岳,张平,谢利德,肖俊. 用新型激光衍射法研究新生在体红细胞变形和取向的变化[J]. 贵阳医学院学报, 2001, 26(1): 1-3 |
| 作者姓名： | 曾柱 杨海岳 张平 谢利德 肖俊 |
| 作者单位： | 1. 贵阳医学院物理教研室, 2. 承德高等师范专科学校, 3. 承德医学院物理教研室, 4. 北京大学基础医学院血液流变研究中心, |
| 基金项目： | 国家自然科学基金资助项目!(39770 2 0 3) |
| 摘 要： | 目的：研究新生在体红细胞变形和取向的变化。方法：用苯肼使动物造成急性溶血性贫血的方法，建立了一种由急性溶血性贫血后而诱发动物幼细胞增多的非正常生理状态的红细胞衰老模型，继而用新型激光衍射法研究新生红细胞在产生到死亡过程中变形和取向能力的改变。结果：对新生红细胞的压积、变形指数、取向指数等指标的连续60多天的监测，发现红细胞在整个衰老过程中的变形指数和取向指数有明显改变。结论：新生红细胞的变形和取向能力比衰老红细胞的变形和取向能力要强。 |
| 关 键 词： | 苯肼类 红细胞变形性 红细胞指数 红细胞比容 取向指数 新型激光衍射法 |
| 文章编号： | 1000-2707(2001)01-0001-03 |
| 修稿时间： | 2000-11-19 |
Variation of the Deformation and Orientation of RBCs in the Course of Erythrocyte Senescence |
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| ZENG Zhu,YANG Hai-yue,ZHANG Ping,XIE Li-De,XIAO Jun. Variation of the Deformation and Orientation of RBCs in the Course of Erythrocyte Senescence[J]. Journal of Guiyang Medical College, 2001, 26(1): 1-3 | |
| Authors: | ZENG Zhu YANG Hai-yue ZHANG Ping XIE Li-De XIAO Jun |
| Abstract: | Objective:To study the deformation and orientation of RBCs under abnormal physiological conditions of phenylhydrazine injection in vivo. Mothods: A models of anemia in rabbits induced by injection of phenylhydrazine was built. To study the deformation and orientation of RBCs with New Ektacytometry. Results: The measurements of hemacrit, deformation index and orientation index etc were performed in the processes of RBC senescence in vivo for more than 60 days. Conclusion: It was shown that there was obvious changes in the RBC's deformation and orientation in the senescent models. The ability to deformation and orientation is better in younger RBCs than in those olders. |
| Keywords: | phenylhydrazines erythrocyte deformability erythrocyte indixes hematocrit orientation indexes new ektacytometry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |