不同方法吻合神经再生情况的比较

①目的　比较不同方式吻合神经的再生情况。②方法　将 72只Wistar大白鼠随机分为 3组 ,每组 2 4只。分别以端端吻合、部分端端吻合、端侧吻合方式吻合颈 7近端与颈 6远端 ,观测手术后 4、8、12、16周各组再生纤维轴突数目及有髓轴突截面积。③结果　术后 4、12、16周部分端端吻合组再生轴突数目及截面积与端端吻合组比较 ,差异无显著性 (F =3.75、3.18,P >0 .0 5 ) ;端侧吻合组术后 4、8、12、16周再生轴突数目及截面积均低于端端吻合组及部分端端吻合组 ,差异有显著性 (F =8.2 3～ 4 5 .71,q=5 .2 5～ 16 .4 8,P <0 .0 5 )。④结论　神经部分端端吻合具有一定的临床应用价值

COMPARISON OF THE NEURAL REGENERATION SITUATIONS AFTER DIFFERENT ANASTOMOTIC PATTERNS

Objective To study the neural regeneration situations after different anastomotic patterns. Methods Seventy-two Wistar rats were randomly divided into three groups, with 24 in each group. The C 7 proximal end and C 6 distal end were anastomosed with partial end-to-end, end-to-end and end-to-side neurorrhaphy, respectively. The six samples in each group were removed respectively at the 4th, 8th ,12th ,and 16th week after the anastomosis. Stained with HE, the regenerated nerve axons and cross section area were calculated. Results The counts and cross section area of the regenerative nerve axons after 4th, 12th, and 16th week showed that the neural regeneration of the partial end-to-end neurorrhaphy group was not significantly different from that of the end-to-end one(F=3.75,3.18;P>0.05), while a significant difference existed between the end-to-side group and the other two groups(F=8.23-45.71,q=5.25-16.48,P< 0.05). Conclusion Partial end-to-end neurorrhaphy is valuable in the clinical application.