冠心病病人代谢综合征的现况调查

目的探讨中国冠心病病人代谢综合征（MS）的流行状况。方法选取中国北方城市（北京市、天津市）,中部城市（上海市、南京市、杭州市、武汉市）和南方（广州市）城市共7个城市52家三级甲等医院为合作研究中心,其心内科2005年6月1日至2005年9月31日间所有符合冠心病诊断纳入标准的住院病人连续入选为研究对象,共收集有效病例3513例。调查内容包括：人体测量学资料、冠心病诊断情况、危险因素、糖代谢状况和血脂代谢状况。结果根据中华医学会糖尿病分会的MS诊断标准,冠心病病人MS患病人数为1064例（30．4％）,男女分别为638例（27．4％）和426例（36．4％）。冠心病病人不同入院方式和不同冠心病种类之间MS的患病率差异无统计学意义（P=0．139,0．446）。另外,北、中、南部城市冠心病病人的MS患病人数为576例（36．5％）、375例（25．5％）和113例（5．1％）。趋势检验显示由北向南呈现降低趋势（x^2=50．252,P〈0．001）。趋势x^2检验,冠心病病人中MS的患病率有明显的年龄趋势,随着年龄的增加MS患病率有增加的趋势（x^2=23．625,P〈0．001）。MS患病率在60岁之前都是男性高于女性,60岁后则女性高于男性,而且上升速度快。结论我国冠心病病人中MS的患病率较高。防治MS对冠心病的发展、预后有着极其重要的意义。

Cross-sectional study on the prevalence of metabolic syndrome in patients with coronary heart disease in China

Objective To investigate the prevalence of metabolic syndrome (MS) in the patients with coronary heart disease (CHD) in China. Methods The clinical data, including anthrometric data, case record form (CRF) , clinical examination, etc. of all CHD patients hospitalized from 1 Jun 2005 to 31 Sep 2005 in the department of cardiology of 52 hospitals in 7 northern, middle, and southern cities in China. A total of 3513 CHD patients, 2341 males and 1172 females, aged 23 -99, were recruited. Results The prevalence of MS was 30. 4% among the 3513 CHD patients, 27. 4% among the males and 36. 4% among the females. The prevalence of MS among the CHD patients in the northern cities was 36. 5% , significantly higher than those in the middle and southern cites (25. % and 25. 1% respectively, X2 = 50. 252 ,P <0. 001) , with a trend to gradually decrease from north to south. The prevalence of MS among the CHD patients receiving acute admission was 28. 8% , not significantly different from that receiving scheduled admission (31. 2% , P =0. 139). There was a clear age-related increase in the prevalence of MS (X2 = 23. 625 , P < 0. 001). The prevalence of MS of the males aged < 60 was higher than that of the females aged < 60; and the prevalence of MS of the females aged > 60 was higher than that of the females aged > 60. Conclusion The prevalence of MS in CHD patients is rather high in China. It is important to screen for MS in patients with high risk for new vascular incidents.