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单纯性肥胖儿童下丘脑-垂体-肾上腺轴的功能状况
引用本文:雷培芸,邓蕾丽,游亚萍. 单纯性肥胖儿童下丘脑-垂体-肾上腺轴的功能状况[J]. 重庆医科大学学报, 1994, 0(1)
作者姓名:雷培芸  邓蕾丽  游亚萍
作者单位:Lei Peiyun,et al Children Hospital
摘    要:通过放射免疫法测定79例单纯性肥胖儿童血清皮质醇及地塞米松抑制试验,并与70例正常儿童比较。发现单纯性肥胖儿童血清皮质醇轻度增高,下丘脑—垂体—肾上腺轴关系平衡,提示单纯性肥胖儿存在肾上腺皮质功能改变。隔夜地塞米松抑制试验与传统的小剂量地塞米松抑制试验比较,其方法简便、结果可靠,尤其适合肥胖儿童门诊筛查。

关 键 词:儿童;单纯性肥胖;皮质醇;地塞米松抑制度验;下丘脑—垂体—肾上腺轴

THE STATE OF HPAFUNCTION IN CHILDREN WITH SIMPLE OBESITY
Lei Peiyun,et al Children Hospital. THE STATE OF HPAFUNCTION IN CHILDREN WITH SIMPLE OBESITY[J]. Journal of Chongqing Medical University, 1994, 0(1)
Authors:Lei Peiyun  et al Children Hospital
Abstract:y radioimmunoassay,serum cortisone level and dexamethasone suppression test in 79 childrenwith simple obesity were dertermined and compared with those in 70 normal children. The resultsshowed that serum cortisone level in ehildren with sunple obesity inereased slightly and therelation of HPAaxis was balanced. It suggests that there has been some change in adrcnal functionin children with sunple obesity. Compared with traditional low dosage dexamethasone suppressiontest,the dexamethasone suppression test of the previous night is simple,accurate and especiallysuitable for screening of obesity children at the outpatient department.
Keywords:Child  Simple Obesity  Cortisone  
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