| 中药化学成分的分子识别与自组装在中药研究中的应用 |
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| 引用本文： | 王蕾,曹雪晓,栗焕焕,王萌,任晓亮.中药化学成分的分子识别与自组装在中药研究中的应用[J].中草药,2020,51(2):516-521. |
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| 作者姓名： | 王蕾 曹雪晓 栗焕焕 王萌 任晓亮 |
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| 作者单位： | 天津中医药大学中药学院, 天津 301617,天津中医药大学中药学院, 天津 301617,天津中医药大学中药学院, 天津 301617,天津中医药大学中医药研究院, 天津 301617,天津中医药大学中药学院, 天津 301617 |
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| 基金项目： | 国家自然科学基金资助项目（81774149） |
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| 摘 要： | 中药化学成分具有独特的结构、众多的修饰位点和丰富的来源,使其容易产生自识别与自组装。这一现象在中药研究中有着广泛的应用前景,可用于揭示中药药性、炮制、配伍理论,提取、分离、富集中药成分,以及研究中药制剂等。综述近年来中药化学成分的分子识别与自组装的研究成果,从其特性及具体应用2个方面展开论述,以期为中药现代化研究拓展思路。
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| 关 键 词： | 中药 药性 炮制 配伍 分子识别 自组装 |
| 收稿时间： | 2019/6/21 0:00:00 |
Application of molecular recognition and self-assembly of chemical components in study of Chinese materia medica |
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| WANG Lei,CAO Xue-xiao,LI Huan-huan,WANG Meng and REN Xiao-liang.Application of molecular recognition and self-assembly of chemical components in study of Chinese materia medica[J].Chinese Traditional and Herbal Drugs,2020,51(2):516-521. |
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| Authors: | WANG Lei CAO Xue-xiao LI Huan-huan WANG Meng and REN Xiao-liang |
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| Institution: | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China,School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China,School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China,Institute of of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China and School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China |
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| Abstract: | Chemical composition of Chinese materia medica (CMM) is easy to occur self-recognition and self-assembly as it has unique structure, many modification sites and abundant sources. The phenomenon has a broad application in the study of CMM. It can be used to reveal the property, processing, compatibility, extraction, separation and enrichment of the components of CMM, and study the preparation of CMM. This paper reviews research results of molecular recognition and self-assembly of chemical components of CMM in recent years, including their characteristics and applications, in order to expend and provide some ideas for the modernization of CMM. |
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| Keywords: | Chinese materia medica drug properties processing compatibility molecular recognition self-assembly |
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