甲状腺功能亢进症患者血清5种元素的测定及意义

目的 :探讨甲状腺功能亢进症病人血清中5种元素的变化及其意义。方法 :用P400等离子发射光谱仪分别检测21例患者血清中锌 (Zn)、铁 (Fe)、钙 (Ca)、镁 (Mg)、铜 (Cu)5种元素 ,同时随机检测21例作正常对照。结果 :弥漫性甲亢 (Graves)病患者血清中Ca、Zn、Cu元素水平明显高于对照组(P<0.01) ,而Fe、Mg元素两组比较无统计学意义。结论 :由于甲状腺功能亢进症患者过多释放甲状腺素导致血清中元素的异常变化 ,此变化既能反应病人机体代谢紊乱程度 ,同时也可以作为病情控制的参考指标。

THE DETERMINATION OF FIVE KINDS OF ELEMENTS IN THE SERUMS OF THE PATIENTS WITH THYROIDISM AND ITS VALUE

Objective: To study the changes of five kinds of elements in the serums of the patients with thyroidism and its significance. Method: The levels of 5 kinds of elements, Zn, Fe, Ca, Mg and Cu, in the serums from 21 cases of thyroidism and 21 health people were measured respectively by P400 isodynamic absorb spectrum. Results: The levels of Ca, Zn and Cu were significantly higher than that of the control group ( P<0.01), while the levels of Fe and Mg didn't show statistical differences compared to the control group. Conclusion: abnormal changes of the elements in the serum result from too much thyroid hormone for the patients; the changes of the elements could indicate the extant of metabolic disorder and may be served as a reference index of patient's state.