注射用多索茶碱与注射用阿洛西林的配伍稳定性考察

目的：考察注射用多索茶碱与注射用阿洛西林的配伍稳定性。 方法：观察及测定注射用多索茶碱与注射用阿洛西林在0.9%氯化钠注射液中配伍后于室温条件下放置6h内的外观及PH值,并采用高效液相色谱法测定配伍液的含量。 结果：与配伍后0h比较,配伍液在6h内的外观和含量都没有明显的变化,而PH值有所浮动。 结论：注射用多索茶碱与注射用阿洛西林在0.9%氯化钠注射液中配伍后于室温下放置6h内质量较稳定。

Study on the Compatible Stability of DoxofyllineInjection and Azlocillin Injection

OBJECTIVE： To study the compatible stability of doxofylline injection and azlocillin injection. METHODS： The changes in appearance and PH value of the mixture of doxofylline injection and azlocillin injection in 0.9% sodium chloride injection within 6 hours at room temperature were observed and detemined,the contect of which determined by HPLC. RESULTS： Compared with the solution at 0h after mixing,no significant changes were found in appearance and content within 6 hours mixing,however,there was a fluctuation in its PH value. CONCLUSION： the mixture of doxophylline and azlocollin in 0.9% Sodium chloride is stable in quality wthinin 6 hours mixing at room temperature.