43例中药制剂药物不良反应分析

目的：了解我院中药制剂的应用及其不良反应的发生情况，为临床安全合理用药提供参考。方法：对2008-2010年上报的中药制剂ADR进行综合分析。结果：在43例ADR中，涉及10种中药制剂，其中以双黄连注射剂发生率最高（69．77％），儿童发生率居多（23．26％），静脉滴注导致ADR发生率最高（83．72％），ADR的症状以皮肤及其附件损害为主（56．52％）。结论：应加强和重视中药制剂ADR监测工作，提高合理用药水平。

Analysis of 43 cases of TCM adverse drug reaction

Objective： To learn the application and adverse drug reaction of TCM in our hospital, so that to provide reference for clinical safety of rational drug use. Methods： To aggregate analysis TCM ADR from 2008 to 2010. Results： 43 cases of ADR involving 10 kinds of TCM, in which, ADR incidence rate of Di-Rhizoma Coptidis injection was 69.77%, ADR incidence rate in children was 23.26%, ADR incidence rate in intravenous drip was 83.72%. The most common symptom of ADR was skin lesion （56.52%）. Conclusion： ADR monitoring must reconstruct to elevate the level of rational administration.