280例不育症男性精奖浆抗精子抗体IgA与精子参数的研究 |
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引用本文: | 辛楠,徐野,王丽梅,魏岩,刘军文. 280例不育症男性精奖浆抗精子抗体IgA与精子参数的研究[J]. 中国优生与遗传杂志, 2009, 17(6): 105-105 |
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作者姓名: | 辛楠 徐野 王丽梅 魏岩 刘军文 |
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作者单位: | 北京军区总医院生殖中心,100007 |
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摘 要: | 目的通过对男性患者精子质量分析,精浆抗精子抗体(antisperm antibodyAsAb)检测,分析精浆中抗精子抗体IgA与精子质量各项参数的相关性的。方法采用禁欲3-7天不育症患者的精液标本检测精子质量,进行精浆抗精子抗体检测.后对检测抗精子抗体阳性抗精子抗体阴性患者分组进行精子质量参数的统计学分析。结果280例不育男性抗精子抗体阳性率为15.35%,其精子的密度/活率活动度/均低于阴性组,两组间存在显著差异(P〈0.01)。结论精浆抗精子抗体IgA与精子密度、活率、精子活力关系密切是男性不育的主要原因之一。
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关 键 词: | 抗精子抗体(ASAb)IgA 精子质量参数 精子密度 精子活率 精子活力 |
The relationship analysis between semen antisperm antibody(AsAb)IgA and Sperm parameters of 280 male infertile patients |
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Affiliation: | XIN Nan, XU Ye, WANG Li - mei, et al. ( The Center of Healthy Birth of Beijing Military area, General Hospital, 100007) |
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Abstract: | Objective: To analyze the relationship between semen antisperm antibody IgA and sperm quality parameters by means of the analysis to sperm quality of male infertile paetients and the measurement to semen antisperm antibody. Methods : To measure sperm quality and antisperm antibody of male infertile patients prevented sexuality for 3 - 7day . Thepatients were distributed into AaAb - positive group and AsAb - negative group. Then we did the statistics analysis to them. Results : The positive rate of AsAb in 280male infertile patients was 15. 35%. Sperm concenteration, motility and a + b grade Sper concentration of AsAb - positive group were lower than that of AsAb - negative group ( P 〈0. 01 ). Conclusions: Semen AsAb IgA is cjose with sperm concentration. Motility and a + b grade sperm concentration. It is one of the main causes of male infertility |
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Keywords: | AsAb IgA Sperm quality parameter Sperm concentration: Soerm motility: a + b grade soerm concentratinn |
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