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Chronic overexpression of corticotropin-releasing factor from the central amygdala produces HPA axis hyperactivity and behavioral anxiety associated with gene-expression changes in the hippocampus and paraventricular nucleus of the hypothalamus
Authors:Flandreau Elizabeth I  Ressler Kerry J  Owens Michael J  Nemeroff Charles B
Institution:a Peptide Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Rd., La Jolla, CA 92037, United States
b Howard Hughes Medical Institute, United States
c Department of Psychiatry and Behavioral Sciences, Yerkes Research Center, Emory University, 954 Gatewood Dr., Atlanta, GA 30329, United States
d Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University, Woodruff Memorial Research Building, Suite 4000, 101 Woodruff Circle, Atlanta, GA 30322, United States
e Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Clinical Research Building, 1120 NW 14th Street, Room 1455 (D-21), Miami, FL 33136, United States
Abstract:
Keywords:Amygdala  Anxiety  Corticotropin-releasing factor (CRF)  Depression  Hypothalamic-pituitary-adrenal (HPA) axis  Lentivirus
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