CT对新生儿缺氧缺血性脑病评价的临床研究

目的:通过CT临床评价新生儿缺氧缺血性脑病(HIE)的颅内特征与临床相关性。方法:收集来我院临床诊断为缺氧缺血性脑病患儿80例,于产后5小时～28天CT扫描,观察其不同时期CT表现的变化。结果:早期(发病0～6天)主要表现为脑内低密度灶、脑实质水肿以及颅内不同部位出血;中期(发病7～14天)前述病灶表现为部分低密度灶好转、出血吸收;15天后为后遗症表现,局部脑萎缩、软化灶形成,部分轻度病例可表现正常。结论:新生儿缺氧缺血性脑病的CT表现随时间变化有其演变过程,正确认识影像表现对临床治疗及预后评估有很大意义。

Clinical research of neonatal hypoxic ischemic enncephalopathy with CT

Objective:To analyse the correlation of CT images in neonates with hypoxic ischemic encephalopathy(HIE) and its clinical manifestation.Methods:CT examination was performed in 80 neonates with HIE in 5 hours to 28 days after their birth.The different CT imaging manifestations at the different stages of HIE were observed and analysed.Results:The lower density,brain edema and hemorrhage were observed in the early stage(0~6 days).The lower density took of favourable turn partially and hemorrhage was absorbed in the middle stage(7~14 days).In the last stage,a part of the neonates returned to normal,while atrophy and softening of the brain were the sequelae in some neonates.Conclusion:CT manifestations of neonatal HIE vary at the different stages,which could help the clinical treatment and appraisal prognosis.