除驳力颗粒联合308 nm 准分子光在面部白癜风患者中的应用效果

目的 探究自制中药剂除驳力颗粒与308 nm准分子光联用在面部白癜风病中的疗效。方法 选取我院2021年1月-2022年1月收治的80例确诊为白癜风疾病的患者为研究对象，根据随机数字表法分为对照组和观察组，各40例。其中对照组采用308 mm准分子光治疗，观察组采用除驳力颗粒联合308 nm准分子光治疗。比较两组治疗效果、复色率以及不良反应发生率。结果 两组治疗后VIDA评分以及VASI评分均低于治疗前，且观察组低于对照组（P ＜0.05）；两组治疗90 d后复色率比较，差异无统计学意义（P ＞0.05）；观察组治疗180 d、270 d复色率高于对照组（P ＜0.05）；观察组不良反应为7.50%，低于对照组的27.50%（P ＜0.05）观察组SAS、SDS评分均低于对照组（P ＜0.05）。结论 除驳力颗粒联合308 nm准分子光治疗稳定期白癜风患者，能够有效控制疾病进展，并促进患者复色、保护皮肤，降低不良反应发生率，提升整体治疗效果，值得临床应用

Application effect of Chuboli Granules Combined with 308 nm Excimer Light in Patients with Facial Vitiligo

Objective To explore the efficacy of self-made traditional Chinese medicine Chuboli granules combined with 308 nmexcimer light in the treatment of facial vitiligo. Methods A total of 80 patients diagnosed with vitiligo in our hospital from January2021 to January 2022 were selected as the research objects. According to the random number table method, they were divided intocontrol group and observation group, with 40 cases in each group. The control group was treated with 308 mm excimer light, and theobservation group was treated with Chuboli granules combined with 308 nm excimer light. The therapeutic effect, repigmentation rateand incidence of adverse reactions were compared between the two groups. Results After treatment, the VIDA score and VASI scoreof both groups were lower than before treatment, and the observation group was lower than the control group (P<0.05). There was nosignificant difference in the rate of 90 d return to normal skin color between the two groups (P>0.05). The rate of 180 d and 270 d returnto normal skin color in the observation group was higher than that in the control group (P<0.05). The incidence of adverse reactions in theobservation group was 7.50%, which was lower than 27.50% in the control group (P<0.05). The SAS and SDS scores of the observationgroup were lower than those of the control group (P<0.05). Conclusion Chuboli granule combined with 308 nm excimer light in thetreatment of stable vitiligo patients can effectively control the disease progression, promote the repigmentation of patients, protectthe skin, reduce the incidence of adverse reactions, and improve the overall treatment effect, which is worthy of clinical application.