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手术治疗顽固性癫痫初探(25例临床分析)
引用本文:张义成,林元相,林启文,陈锦峰,王晨阳.手术治疗顽固性癫痫初探(25例临床分析)[J].福建医科大学学报,1994(3).
作者姓名:张义成  林元相  林启文  陈锦峰  王晨阳
作者单位:福建医学院附属第一医院神经外科,福建医学院附属第一医院脑电图室
摘    要:随访观察开颅手术治疗顽固性癫痫25例,病程平均8.4年。术前平均服抗痫药治疗5.2年。皮质电图监测下行颞叶前份+杏仁核切除12例;颞叶外皮层痫灶切除3例;病灶+周围皮层痫灶切除9例;胼胝前部切开1例。无明确病因者占64%。痫灶光镜和电镜检查(11例)结果符合癫痫的病理改变。随访结果,痊愈及显效者占84%,总有效率96%,无效4%。无手术死亡。

关 键 词:顽固性癫痫,手术,皮质电图

Preliminary Study on Surgical Treatment of Intractable Epilepsy (Analysis of 25 Cases)
Zhang Yicheng, Lin Yuanxiang, Lin Qiwen,et al.Preliminary Study on Surgical Treatment of Intractable Epilepsy (Analysis of 25 Cases)[J].Journal of Fujian Medical University,1994(3).
Authors:Zhang Yicheng  Lin Yuanxiang  Lin Qiwen  
Abstract:This paper reports the operative results of 25 cases of intractable epilepsy, The mean course of all cases was 8.4 years. All these patients took antiepileptics for 5.2 years on the average before operation. All the operations were performed with intra-operative electrocorticography surveilliance. Anterior temporal lobectomy and amygdalectomy were performed on 12 cases, resection of the cortical focus outside the temporal lobe on 3 cases, removal of the causative lesion and the epileptogenic focus on 9 cases, callsotomy on one case. There was no operative mortality. No causative lesion was found in 64%of these cases. But their epileptogenic focuses manifested epileptic pathological changes under light and electron microscope, Follow-up data showed execllent result: 84%of cases were cured or significantly improved: the total effective rate was 96%, Some questions about location of the focus and the mode of operation are analysed in this paper.
Keywords:epilepsy  Intractable  surgery  electrocorticography
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