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Octreotide-induced hypoxemia and pulmonary hypertension in premature neonates
Authors:Arevalo R P  Bullabh P  Krauss A N  Auld P A M  Spigland Nitsana
Affiliation:From The New York Presbyterian Hospital, Weill Medical College of Cornell University, New York, NY.
Abstract:The authors report 2 cases of premature neonates who had enterocutaneous fistula complicating necrotizing enterocolitis. Pulmonary hypertension developed after administration of a somatostatin analogue, octreotide, to enhance resolution of the fistula. The authors discuss the mechanism of the occurrence of this complication and recommend caution of its use in high-risk premature neonates. J Pediatr Surg 38:251-253.
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