| 牙龈卟啉菌内毒素诱导人牙周纤维细胞释放细胞因子的实验研究 |
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| 引用本文： | 李颖超,马良,谢玮,布静秋,郝秀华,颜光涛. 牙龈卟啉菌内毒素诱导人牙周纤维细胞释放细胞因子的实验研究[J]. 军医进修学院学报, 1999, 0(1): 48-49 |
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| 作者姓名： | 李颖超 马良 谢玮 布静秋 郝秀华 颜光涛 |
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| 作者单位： | 1. 解放军总医院口腔科,北京,100853
2. 解放军总医院生物化学研究室 |
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| 基金项目： | “九五”军队医药卫生科研基金 |
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| 摘 要： | 目的：研究牙龈卟啉菌内毒素诱导人牙周纤维细胞释放白细胞介素６（ＩＬ－６）和肿瘤坏死因子（ＴＮＦ）的影响。方法：放射免疫检测法。结果；表明人牙周纤维细胞在牙龈卟啉菌内毒素作用下释放ＩＬ－６，而不能释放ＴＮＦ。结论：人牙周纤维细胞释放ＩＬ－６的量与内毒素的浓度和作用的时间有关。
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| 关 键 词： | 细胞因子 脂多糖 牙周纤维细胞 |
Cytokine production ofhuman periodontal ligament cells stimulated by porphyromonas gingivalis lipopolysaccharide |
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| Li Yingchao,ma liang,Xie Wei,Bu Jingqiu,hao Xiuhua,Yan Guangtao. Cytokine production ofhuman periodontal ligament cells stimulated by porphyromonas gingivalis lipopolysaccharide[J]. Academic Journal of Pla Postgraduate Medical School, 1999, 0(1): 48-49 |
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| Authors: | Li Yingchao ma liang Xie Wei Bu Jingqiu hao Xiuhua Yan Guangtao |
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| Abstract: | Objective: To reseach the function of human preiodontal ligament cell productions interleukin 6 (IL 6) and tumor necrosis factor (TNF) in response to porphyromonas gingivalis lipopolysaccharide (P.G LPS). Methods: IL 6 and TNF was measured by radioimmunoassay. Results:IL 6 was released from human preiodontal ligament cells stimulated by P. g LPS, but TNF was not produced. Conclusion:The amount of IL 6 is related with the concentration of P.g LPS in cell culture medium and the time of action. |
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| Keywords: | cytokine endotoxins preiodontal fibroblast cells |
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