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Predominance of capsular polysaccharide type 5 among oxacillin-resistant Staphylococcus aureus.
Authors:J M Fournier  A Bouvet  A Boutonnier  A Audurier  F Goldstein  J Pierre  A Bure  L Lebrun  and H K Hochkeppel
Institution:Institut Pasteur, Paris, France.
Abstract:The relationship between capsular polysaccharide types 5 and 8 and resistance of Staphylococcus aureus to oxacillin was studied with a collection of 406 clinical isolates from six French hospitals. Of 175 type 5 isolates, 84 (48%) were resistant to oxacillin. In contrast, only 8 of 160 type 8 isolates (5%) and 5 of 71 nontypeable isolates (7%) were resistant to oxacillin. Therefore, capsular typing of clinical isolates of S. aureus may facilitate the choice of first-line antibiotic therapy.
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