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速尿吸入对哮喘患者肺功能与气道反应性的影响
引用本文:冯起校,何双兰,李志波.速尿吸入对哮喘患者肺功能与气道反应性的影响[J].中国实用内科杂志,2004,24(9):547-548.
作者姓名:冯起校  何双兰  李志波
作者单位:广东中山市陈星海医院内一科,528415
摘    要:目的 研究速尿吸入对哮喘患者肺功能与气道反应性的影响。方法 采用双盲随机方法 ,治疗组每次吸入速尿 (2 0mg ,每日 2次 )及其赋形剂 ;对照组仅吸入其赋形剂。结果 观察治疗 10d后 ,治疗组肺功能除个别指标外 ,均有不同程度改善 ,其中肺活量 (VC)、用力肺活量 (FVC)与第 1秒钟用力呼气容积 (FEV1)改善有显著意义。对照组治疗后肺功能也能获得一定改善 ,但均无统计学意义。结论 速尿雾化吸入可缓解哮喘 ,也对阐明药物治疗机理和哮喘发病的病生机理增添了新内容。

关 键 词:支气管哮喘  速尿吸入  呼吸功能试验  气道高反应性
文章编号:1005-2194(2004)09-0547-02
修稿时间:2004年2月26日

The effect of inhalation of furosemide on lung function and airway hyperresponsiveness in asthmatic patients
Feng Qixiao,He Shuanglan,Li Zhibo.The effect of inhalation of furosemide on lung function and airway hyperresponsiveness in asthmatic patients[J].Chinese Journal of Practical Internal Medicine,2004,24(9):547-548.
Authors:Feng Qixiao  He Shuanglan  Li Zhibo
Affiliation:Feng Qixiao,He Shuanglan,Li Zhibo.The First Department of Internal Medicine,Chen Xinhai Hospital of Zhongshan,Zhongshan 528415,China
Abstract:Objective To evaluate the effect of inhalation of furosemide on lung function and airway hyperresponsiveness in asthmatic patients.Methods By double blind randomized controlled trial,the effect of inhalation of furosemide (20mg twice daily) on the lung function and airway hyperresponsiveness in the asthmatics was studied.Results Most of lung function tests of the observation group improved 10 days after inhalation therapy.The improvement of VC,FVC and FEV 1 was significant statistically.There was also slight improvement of lung function in the control group,but not statistically significant.but it was decreaded slass.Conclusion Asthma can be relieved by inhalation of furosemide.
Keywords:Bronchial asthma  Furosemide inhalation  Respiratory fundtion tests  Airway hyperresponsiveness  
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