骨折并发脂肪栓塞综合征12例临床分析

目的：探讨骨折并发脂肪栓塞综合征早期治疗的意义及方法。方法：对1995年至2003年间治疗的骨折并发脂肪栓塞综合征12例进行了分析和评价。结果：12例病人，治愈及好转11例，出院时1例偏瘫，其余10例神经系统均完全恢复。死亡1例，死亡原因：创伤性休克，合并多器官功能衰竭。结论：通过对12例临床观察分析及文献阅读，认为正确处理骨折、观察动脉血氧分压变化、治疗脑缺氧及合理采用激素是治疗本征的有效方法。骨折并发脂肪栓塞综合征需要综合分析临床表现与辅助检查，确诊后经早期综合治疗，对一些多发性骨折及多发损伤性病人需要严密观察，以减少死亡率。

12 Cases of Fracture with Fat Embolism Syndrome

Objective: To discuss the significance of earlier diagnosis and treatment of fat embolism syndrome (FES) caused by severe fracture of long bone or pelvis.Methods: 12 FES patients treated from 1995 to 2003 were analyzed and evaluated.Results: One patient died of traumatic shock with function failure of multiple organs,the rest were cured and improved,one with hemiplegia.Conclusion: According to the observation of 12 cases and other references,the author believed that proper treatment of fracture,oxygen and blood pressure,brain lacking of oxygen and proper use of hormone was effective for FES.Synthetically analyzing clinical symptoms and adjuvant examinations were necessary for FES.Earlier synthetical treatment and close observation of the patients with multiple fracture and multiple hurt may be necessary to reduce the death rate.