达英-35配合右归丸加减治疗多囊卵巢综合征临床观察

目的 探讨中西医结合治疗多囊卵巢综合征的临床效果。方法 采用随机对照的方法将63例多囊卵巢综合征患者分为中西药组（32例）、西药组（31例）。西药组以口服达英-35（Diane-35）治疗；中西药组在西药组的基础上加服右归丸加减。观察治疗前、治疗3个周期后及治疗停药后第6个周期患者体内相关的内分泌激素及临床症状体征的变化。结果 治疗3个周期后两组患者的内分泌激素水平和B超检查指标均明显改善，但停药后第6周期，西药组又恢复到治疗前的水平和状况，而中西药组仍保持治疗后的水平和状况（P〈0．01），且月经恢复正常，排卵恢复及妊娠率明显高于西药组（P〈0．01）。结论 中西医结合在治疗多囊卵巢综合征中不但能收到近期明显效果，而且能使疗效得到巩固。

Clinical Research on Combined Therapy of Diane-35 with Modified Yougui Pill on Polycystic Ovarian Syndrome

ObjectiveTo investigate the clinical efficacy of integrative traditional Chinese and Western medicine on polycystic ovarian syndrome (PCOC). MethodsSixty-three patients with polycystic ovarian syndrome were randomly allocated into 2 groups, 31 patients orally administered with diane-35 in the Western medicine group (WMG) and 32 patients treated with conventional controlled medicine plus modified Yougui Pill in the integrative medicine group (IMG). Changes of relevant hormones and clinical syndromes in patients were detected before treatment, after 3 cyclic treatment and at the 6th cycle after treatment. ResultsThe levels of relevant hormones and the indexes of B-ultrasonic were obviously improved after treatment in the two groups. But 6 cycles after treatment, these changes restored to the baseline as those before treatment in WMG, while maintained in IMG (P<0.01). What's more, the normalization of menstruation, ovulation and pregnancy rate in IMG were significantly higher than those in WMG (P<0.01). ConclusionDiane-35 combined with modified Yougui pill in treating polycystic ovarian syndrome not only shows marked short-term effect, but could consolidate the curative effect.