Converting enzyme inhibitors (captopril,enalapril, perindopril) prevent early-post infarction ventricular fibrillation in the anaesthetized rat |
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Authors: | C Ribuot L Rochette |
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Institution: | (1) Laboratoire de Pharmacodynamie et de Physiologie Pharmaceutique, Faculté de Pharmacie-Université de DIJON-7 Bd. J.d'Arc 21000, Dijon, France |
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Abstract: | Summary The angiotensin-converting enzyme inhibitors, captopril, enalapril and perindopril, exert antiarrhythmic effects on early post-infarction arrhythmias in anaesthetized rats. These studies support the hypothesis that converting enzyme inhibitors could have a cardioprotective effect, but the doses used are probably high in relation to those therapeutically applicable to man. |
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Keywords: | converting enzyme inhibitors antiarrhythmic effects |
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