Detection and Management of Hypothyroidism Following Thyroid Lobectomy: Evaluation of a Clinical Algorithm期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Detection and Management of Hypothyroidism Following Thyroid Lobectomy: Evaluation of a Clinical Algorithm

Authors:	Johner Amanda Griffith Obi L Walker Blair Wood Leanne Piper Hannah Wilkins Graeme Baliski Christopher Jones Steven J M Wiseman Sam M

Institution:	(1) Department of Surgery, St. Paul’s Hospital & The University of British Columbia, Vancouver, BC, Canada;(2) Department of Medical Genetics, University of British Columbia, British Columbia Cancer Agency, Vancouver, BC, Canada;(3) Michael Smith Genome Sciences Center, Vancouver, BC, Canada;(4) Department of Endocrinology, St. Paul’s Hospital & The University of British, Columbia, Vancouver, BC, Canada;(5) Department of Pathology & Laboratory Medicine, St. Paul’s Hospital & The University of British Columbia, Vancouver, BC, Canada;(6) Department of Surgery, Kelowna General Hospital, Kelowna, BC, Canada;

Abstract:	Background The objectives of this study were to determine: (1) the incidence permanent hypothyroidism after thyroid lobectomy (TL), (2) whether asymptomatic patients with mildly elevated thyrotropin (TSH) levels can be managed without thyroid hormone replacement, and (3) if the degree of lymphocytic infiltration (LI) and germinal center (GC) formation in the resected thyroid lobe correlates with the development of post-TL hypothyroidism.

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