Plasma catecholamine concentrations—changes after infiltration with local anaesthetic solutions and adrenaline during bat-ear surgery |
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| Authors: | J. K. L. Lew FFARCS K. A. Mobley FFARCS K. J. Achola MSc G. Smith MD FFARCS |
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| Affiliation: | University Department of Anaesthesia, Leicester Royal Infirmary. |
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| Abstract: | Plasma catecholamine concentrations were measured in 12 patients who had bilateral bat-ear surgery following infiltration of each ear with 2 ml 2% lignocaine with adrenaline 1:100,000. Venous blood samples were withdrawn before and at set intervals after infiltration. Plasma adrenaline concentration increased from 0.8 pmol/ml to a peak of 2.2 pmol/ml at 2 minutes after infiltration; this is an increase of 175%. There was no significant change in plasma noradrenaline concentration. |
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| Keywords: | Anaesthetics, local lignocaine Sympathetic nervous system catecholamines, sympathomimetic agents |
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