| 多西他赛联合卡培他滨化疗治疗进展期胃癌术后的研究 |
| |
| 引用本文： | 黄志强,陈森林,钱钢,宋东华,郭飞,刘胜. 多西他赛联合卡培他滨化疗治疗进展期胃癌术后的研究[J]. 现代中西医结合杂志, 2011, 20(9): 1041-1043 |
| |
| 作者姓名： | 黄志强 陈森林 钱钢 宋东华 郭飞 刘胜 |
| |
| 作者单位： | 解放军第411医院,上海,200081 |
| |
| 摘 要： | 目的探讨进展期胃癌根治术后予以多西他赛联合卡培他滨化疗的疗效及耐受性。方法 126例进展期胃癌根治术后患者随机分为2组,试验组63例采用多西他赛(TXT)+卡培他滨方案化疗,对照组63例采用TXT+奥沙利铂+5-氟尿嘧啶/CF方案化疗,比较2组的不良反应发生率及1 a、3 a生存率。结果试验组1 a及3 a生存率分别为81%和62%,对照组分别为60%和38%,2组1 a及3 a生存率比较均有显著性差异(P均<0.05)。试验组不良反应发生率为76%,对照组为44%,2组比较无显著性差异(P>0.05)。结论进展期胃癌根治术后采用TXT联合卡培他滨方案化疗能显著提高患者的1 a及3 a生存率,且患者容易耐受。
|
| 关 键 词： | 进展期胃癌 化疗 多西他赛 卡培他滨 |
Study on docetaxel plus capecitabine in treatment of advanced gastric carcinoma postoperation |
| |
| Huang Zhiqiang,Chen Senlin,Qian Gang,Song Donghua,Guo Fei,Liu Sheng. Study on docetaxel plus capecitabine in treatment of advanced gastric carcinoma postoperation[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2011, 20(9): 1041-1043 |
| |
| Authors: | Huang Zhiqiang Chen Senlin Qian Gang Song Donghua Guo Fei Liu Sheng |
| |
| Affiliation: | Huang Zhiqiang,Chen Senlin,Qian Gang,Song Donghua,Guo Fei,Liu Sheng(The 411th Hospital of PLA,Shanghai 200081,China) |
| |
| Abstract: | Objective It is to investigate the curative effect and toleration of docetaxel plus capecitabine in the treatment of advanced gastric carcinoma post-operation.Methods 126 patients with advanced gastric carcinoma after radical gastrectomy were randomly divided into two groups: 63 cases in test group were received docetaxel plus capecitabine chemotherapy;63 cases in control group were received docetaxel plus L-OHP and 5-FU/CF chemotherapy.The side effect and 1-and 3-year survival rates were compared between b... |
| |
| Keywords: | advanced gastric carcinoma chemotherapy docetaxel capecitabine |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
