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坦索罗辛和硝苯地平治疗远端输尿管结石的疗效比较
引用本文:廖泽明,王超,陈志强,叶章群.坦索罗辛和硝苯地平治疗远端输尿管结石的疗效比较[J].现代中西医结合杂志,2011,20(9):1046-1047,1050.
作者姓名:廖泽明  王超  陈志强  叶章群
作者单位:1. 湖北省荆门市第一人民医院,湖北,荆门,448000
2. 华中科技大学同济医学院附属同济医院,湖北,武汉,430030
摘    要:目的比较坦索罗辛与硝苯地平治疗末端输尿管结石的排石效果。方法将输尿管末端结石患者112例随机分成2组,坦索罗辛组59例,采用坦索罗辛联合应用抗生素(喹诺酮类)和必要的镇痛药物(双氯芬酸钠栓塞肛或加用度冷丁)治疗,硝苯地平组53例采用硝苯地平联合应用抗生素和必要的镇痛药物治疗。以结石排出或治疗随访满28 d作为疗效观察终点。结果与硝苯地平组比较,坦索罗辛组排石率显著提高,排石速度明显加快,使用镇痛药物的次数显著减少,接受住院或输尿管镜治疗的人数明显减少。而在排出结石的直径和药物的不良反应方面,2组比较没有显著性差异。结论坦索罗辛治疗输尿管末端结石有较高的排石成功率,缩短了排石时间,降低了肾绞痛的发生几率,能改善患者的生活质量,减少对住院或接受输尿管镜治疗的需求,适合输尿管末端结石患者的家庭治疗。

关 键 词:坦索罗辛  硝苯地平  输尿管结石

Comparison of therapeutic effect of tamsulosin and nifedipine in treatment of distal ureteral calculus
Liao Zeming,Wang Chao,Chen Zhiqiang,Ye Zhangqun.Comparison of therapeutic effect of tamsulosin and nifedipine in treatment of distal ureteral calculus[J].Modern Journal of Integrated Chinese Traditional and Western Medicine,2011,20(9):1046-1047,1050.
Authors:Liao Zeming  Wang Chao  Chen Zhiqiang  Ye Zhangqun
Institution:Liao Zeming1,Wang Chao1,Chen Zhiqiang2,Ye Zhangqun2 (1.The First People's Hospital of Jingmen,Jingmen 448000,Hubei,China,2.Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,China)
Abstract:Objective It is to evaluate the clinical effect of tamsulosin and nifedipine in the treatment of distal ureteral stones.Methods 112 patients with distal ureteral calculus were randomly divided into 2 groups.In study group,59 cases were treated with tamsulosin 0.4 mg daily plus antibiotic(quinolones) and pain-killer(diclofenac sodium or pethidine).In control group,53 cases were treated with nifedipine slow-release 20 mg daily in addition to the same drugs as used in study group.Ultrasound or radiology follow...
Keywords:tamsulosin  nifedipine  ureteral calculus  
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