| 基于纤支镜刷片细胞学的肺癌细胞核形态的多参数定量研究 |
| |
| 引用本文： | 龚平,郭华雄,王文清,赵廷宽,李春燕.基于纤支镜刷片细胞学的肺癌细胞核形态的多参数定量研究[J].中国体视学与图像分析,2011(2):152-155. |
| |
| 作者姓名： | 龚平 郭华雄 王文清 赵廷宽 李春燕 |
| |
| 作者单位： | 华中科技大学同济医学院附属荆州医院病理科(荆州市中心医院); |
| |
| 基金项目： | 荆州市医疗卫生科技发展计划项目(2009-13-19) |
| |
| 摘 要： | 目的探讨基于纤维支气管镜刷片细胞涂片中,多参数的细胞核形态定量分析对肺癌的鉴别价值。方法采用回顾性的分析方法,利用HMIAS-2000医学图文分析测量系统,对组织学确诊的纤维支气管镜刷片的细胞核进行形态定量研究(腺癌48例、鳞癌28例、小细胞癌22例,阴性对照组40例)。结果在22个形态定量参数中,19项参数有显著统计学差异(P<0.01),2项有统计学差异(P<0.05),1项无统计学差异(P>0.05)。结论多参数的形态计量揭示了纤支镜刷片细胞学的肺癌与肺良性病变细胞核形态学计量特征,对辅助鉴别诊断良恶性具有一定的意义。
|
| 关 键 词： | 纤支镜刷片 细胞学 肺癌 细胞核 多参数 定量研究 |
A multi-parameter morphometric analysis of lung cancer cell nuclei on bronchoscopic brush cytology smears |
| |
| GONG Ping,GUO Huaxiong,WANG Wenqing,ZHAO Tingkuan,LI chunyan.A multi-parameter morphometric analysis of lung cancer cell nuclei on bronchoscopic brush cytology smears[J].Chinese Journal of Stereology and Image Analysis,2011(2):152-155. |
| |
| Authors: | GONG Ping GUO Huaxiong WANG Wenqing ZHAO Tingkuan LI chunyan |
| |
| Institution: | GONG Ping,GUO Huaxiong,WANG Wenqing,ZHAO Tingkuan,LI chunyan(Affiliated Jingzhou Hospital,Tongji Medical College of Huazhong University of Science and Technology,Jingzhou 434020,China) |
| |
| Abstract: | Objective To evaluate the value of multi-parameter morphometric analysis of cell nuclei obtained by bronchoscopic brush cytology in differential diagnosis of lung cancer.Methods Brush cytology smears were obtained by bronchofiberscopy from 98 cases of lung cancers and 40 benign lung lesions,and processed with Wright-Giemsa staining.22 morphometric parameters were used for measurement using a HMIAS-2000 image analysis system,and the results were statistically analyzed to evaluate the value in differential di... |
| |
| Keywords: | bronchoscopic brush cytology smears lung cancer cell nucleus morphometry |
| 本文献已被 CNKI 维普 等数据库收录！ |
