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普罗布考对颈动脉粥样硬化斑块作用的临床研究
引用本文:张宝红,刘改云,王光耀. 普罗布考对颈动脉粥样硬化斑块作用的临床研究[J]. 包头医学院学报, 2009, 25(5): 49-51
作者姓名:张宝红  刘改云  王光耀
作者单位:包头第四医院心内科,内蒙古,包头,014030
摘    要:目的:为探讨普罗布考对颈动脉粥样硬化斑块的影响。方法:对50例冠心病患者采用彩色多普勒仪测定口服普罗布考12周前、后颈动脉粥样斑块的大小,同时,检测服药前、后血清总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇。结果:12周后,颈动脉粥样斑块明显缩小。普罗布考对甘油三酯无明显影响,但是血清总胆固醇及低密度脂蛋白胆固醇均明显降低。结论:普罗布考可稳定或缩小颈动脉粥样斑块,对冠心病的防治具有重要的临床意义。

关 键 词:普罗布考  动脉粥样硬化  斑块

A Clinical Study of Effect of Probucol on Carotid Atherosclerosis Plaque
ZHANG Baohong,LIU Gaiyun,WANG Guangyao. A Clinical Study of Effect of Probucol on Carotid Atherosclerosis Plaque[J]. Journal of Baotou Medical College, 2009, 25(5): 49-51
Authors:ZHANG Baohong  LIU Gaiyun  WANG Guangyao
Affiliation:ZHANG Baohong,LIU Gaiyun,WANG Guangyao (Department of Cardiovascular Medicine,The Forth Hospital of Baotou,Baotou 014030,China)
Abstract:Objective: To explore the effect of Probucol on carotid atherosclerosis plaque.Methods: Carotid atherosclerosis plaque were measured by color Dopplar in 50 patients with coronary heart disease 12 weeks before and after administration of Probucol(orally).Meanwhile,serum total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C)and low density lipoprotein cholesterol(LDL-C)were determined as well by routine.Results: At the end of 12 weeks,the carotid atherosclerosis plaque decreased ma...
Keywords:Probucol  Atherosclerosis  Plaque  
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