白血病及重型再生障碍性贫血并发败血症40例临床分析

对白血病化疗后并发败血症35例及重型再生障碍性贫血并发败血症5例进行了分析,发现G杆菌占92％,原发感染灶中软组织较多,败血症时血清CRP明显升高,外周血中性粒细胞绝对值减少;应用普通抗生素组绿脓杆菌、大肠杆菌败血症多,治愈率41％,第三代头孢霉素组绿脓杆菌、克雷白杆菌败血症多,治愈率72％,两组病例治愈率差异显著(P

Analysis of Forty Cases of Sepsis in Children with Leukemia or Severe Aplastic Anemia

Thirty-five cases with leukemia and five caseswith severe aplastic anemia were both complicatedwith sepsis. Ninety two percent of the cases werecaused by Gram. negative bacteria, mainlyPs. Aeruginosa, Escherichia Coli and Klebsiella Pneu-monia. Serum C-reactive protein were all rose andperipheral neutrophii count all decreased. Seventy onepercent in twenty two cases who were treated withCeftriaxone or Ceftazidine were cured, as comparedwith forty one percent in eighteen cases of those givenantibiotics without Ceftriaxone or Ceftazidine, Theseresults suggest that Ceftriaxone and Ceftazidine aremore effective for sepsis in children with leukemia orsevere aplastic anemia.