| Abstract: | Some functional properties of interferon and of a factor inhibiting migration of macrophages (MMIF), obtained by stimulation of human tonsillar lymphocytes by Newcastle disease virus (NDV) or streptolysin O, were investigated. Both interferon and MMIF were shown to inhibit migration of human tonsillar cells actively, but they differed in their antiviral activity and their sensitivity to heating to 56°C for 30 min, MMIF production reached its maximum later than interferon production. Stimulation of human tonsillar lymphocytes by NDV led to the production of a broader spectrum of mediators of hypersensitivity of delayed type than stimulation by streptolysin O.Laboratory of Physiology and Pathophysiology and Laboratory of Virology, Kiev. Scientific-Research Institute of Otolaryngology. (Presented by Academician of the Academy of Medical Sciences of the USSR, L. V. Gromashevskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 3, pp. 302–303, March, 1977. |
