黄芪精泡腾片的生产工艺

［摘要］目的研究制备黄芪精泡腾片的生产工艺。方法正交法优选黄芪药材提取工艺；以崩解时限、粘冲强度、口感等为评价指标，采用单因素实验优选成型工艺。结果确定最佳工艺条件为：药材浸渍后收集8倍渗滤液，渗滤速度为每1 kg药材5.00～6.25 mL•min 1，浓缩成浸膏，加糊精干燥；选用枸橼酸和碳酸氢钠作为泡腾剂，内加羧甲淀粉钠（CMS Na），外加预胶化淀粉作为崩解剂，所得泡腾片口感好，硬度适中，吸湿性良好，片重差异小，崩解时限符合规定。结论该制备工艺稳定，可行。

The Preparation Process of Huangqijing Effervescent Tablets

Objective To study preparation technics of huangqijing effervescent tablets.Methods The optimum extraction technics of radix astragal was selected by orthogonal test and tiptop molding technics was screened out through single factor test such as disintegration time and taste.Results The best preparation process was that 8 times of percolation liquid was gathered,percolation speed was 5.00-6.25 mL per minute,percolation yield was inspissated,and then dried using dextrin.At last,aluminum citrate and sodium bicarbonate as effervescent materials and CMS-Na and pregelatinized starch as disintegrating agent were applied.Conclusion Our preparation procedure was optimum and simple.