459例神经鞘瘤多发部位临床分析

目的研究神经鞘瘤的流行病学和不同部位分布情况，为防治这一临床常见软组织肿瘤提供参考资料。方法统计本院2002年1月-2012年6月住院手术并经过病理学证实的459例神经鞘瘤患者的流行病学和治疗学资料，按照流行病学、各部位发病率等进行分别统计。结果神经鞘瘤男女比例为1：1．20，颅神经鞘瘤发病率占全身发病率的53．59％，颅神经发病中桥小脑角占86．99％。椎管内神经鞘瘤排第2位。占神经鞘瘤全身发病率的40．52％，颈椎、胸椎和腰椎为56：49：58，即发病顺序为颈椎〉腰椎〉胸椎〉其他。病理上可见多种改变。如坏死、囊变、液化和细胞丰富等。结论神经鞘瘤是一种常见的住院治疗疾病．通过流行病学的统计可对神经鞘瘤的发病率和分布情况进行了解，同时认为颅神经鞘瘤最为常见，其次为颈椎神经并以颈椎为主。

Clinical Analysis on 459 Cases of Schwannom Multiple Sites

bstract OBJECTIVE To study the epidemiology and schwannomas different parts of the distribution, in order to combat this common clinical soft tissue tumors provided references. METHODS From January of 2002 to June of 2012, inpatient surgery pathology confirmed 459 cases of schwannoma patients epidemiological and therapeutic data, in accordance with the epidemiology, incidence rates for each part separately statistics. RESULTS The male to female ratio schwannoma 1：1.20, cranial nerve sheath tumor incidence rate accownt 53.59% of systemic morbidity, cranial nerve disease in the cerebellopontine angle and accounted 86.99%. Spinal schwannomas ranked second, accounting for 40.52% of schwannoma systemic morbidity, cervical： thoracic： lumbar spine is 56：49：58, that the order of the incidence of cervical〉 lumbar〉 thoracic〉 other. Visible on a variety of pathological changes such as： necrosis, cystic degeneration, liquefaction, cell-rich and so on. CONCLUSION Schwannoma was a common disease hospitalization, through epidemiological statistics available on the incidence of schwannomas and distribution had considerable understanding, but that the cranial nerves the most common, followed by cervical nerve and cervical based.