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刺五加多甙对胃缺血再灌注损伤防护作用的实验研究
引用本文:郑日男,裴风郁,朴熙绪,金海燕. 刺五加多甙对胃缺血再灌注损伤防护作用的实验研究[J]. 中国中西医结合杂志, 1998, 0(Z1)
作者姓名:郑日男  裴风郁  朴熙绪  金海燕
作者单位:吉林省延边医学院附属医院 吉林133000
摘    要:目的:观察刺五加对胃缺血再灌注损伤的防护作用。方法:采用家兔胃缺血再灌注模型。结果:刺五加维持缺血及再灌注期 SOD 活力,减少 MDA 含量,减轻缺血再灌注后胃粘膜病理损伤。结论:刺五加通过消除和抑制胃缺血再灌注时氧自由基产生,提高组织抗氧化能力,对胃缺血灌注损伤起到保护作用。

关 键 词:刺五加  超氧化物歧化酶  丙二醛  胃粘膜损害

Experimental Study on Effect of Eleutheroside in Protecting Gastric Ischemia-Reperfusion Injury
Zheng Rinan Pei Fengyu Piao Xixu The Affiliated Hospital of Yanbian Medical College,Jilin. Experimental Study on Effect of Eleutheroside in Protecting Gastric Ischemia-Reperfusion Injury[J]. Chinese journal of integrated traditional and Western medicine, 1998, 0(Z1)
Authors:Zheng Rinan Pei Fengyu Piao Xixu The Affiliated Hospital of Yanbian Medical College  Jilin
Abstract:Objective:To observe the effect of Eleulheroside in protecting gastric ischemia-reperfusion injury.Methods:The gas- tric ischemia-reperfusion model of rabbits was used.Results:Eleutheroside could retain the SOD activity in ischemic or reperfusion period,reduce the content of malondialdehyde,and relieve the pathologic gastric mucosa injury induced by is- chemia-reperfusion.Conclusion:Eleutheroside could protect the gastric ischemia-reperfusion injury by eliminating and in- hibiting production of oxygen free radical during gastric ischernia-reperfusion and enhancing the anti-oxidizing ability of tis- sues.
Keywords:Eleutheroside  superoxide dismutase  malondialdehyde  gastric mucosa injury
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